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A network meta-analysis published in 2025 confirmed retatrutide demonstrated greater absolute weight reduction compared to tirzepatide across comparable timeframes

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The best dose is the one that matches your current activity level, goals, and tolerance taken consistently, at the right time, as part of a broader health approach

At the same time, there settings do not put the epidermis at risk as the epidermis is a much larger target than a hair follicle and would require significantly higher settings to overheat