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Using human liver microsomes, it was also recently reported that sulforaphane metabolites (0-200 M) had little-to-no effect on the activities of CYP1A2, CYP2B6, CYP2D6, and CYP3A4 (23)

In summary, we propose that the regulation of neuronal and neuronal ferroptosis by targeting Nrf2 is expected to become a new direction for the prevention and treatment of neurodegenerative diseases

This presents with a combination of sensory ataxia, spastic weakness, and loss of vibration and position sense

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