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Almost every result we promise lives inside that 24-week window, and the protocol, depth, density, energy, number of passes, downtime requested, has to map cleanly onto that biology

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Therefore, a combination of transcellular and paracellular routes for crossing the nasopharyngeal barrier is also possible if the meningococci crossing via the transcellular route induce a sufficient level of inflammation to alter epithelial permeability, allowing other bacteria to follow the paracellular route

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This toxicity is characterized by elevated levels of markers of oxidative stress and neurotoxicity, as well as spikes in glucocorticoid levels