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Proteins and peptides have imperfect absorption due to their critical physicochemical properties, including susceptibility to enzymatic degradation and poor permeability across intestinal mucosal membranes.[] The current study was planned to evaluate various DDS routes proposed for the distribution of proteins and peptides in terms of both parenteral and nonparenteral delivery systems

In those mouse studies, the researchers injected the peptide and found that it was able to cross the blood-brain barrier and reach neurons of the hippocampus and other parts of the brain

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