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Withdrawal symptoms span multiple domains and can include psychological symptoms such as marked anxiety, panic attacks, irritability, agitation, depressed mood, and intrusive worry

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A study where small molecule, REV-ERB agonists like SR9011 and SR9009 and were used showed that they could repress certain processes like metabolism, cell proliferation, and inflammation that are required for tumorigenesis (Scheiermann et al., 2013)

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Secukinumab, a human anti-interleukin-17A monoclonal antibody, in patients with psoriatic arthritis (FUTURE 2): a randomised, double-blind, placebo-controlled, phase 3 trial