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The induction of apoptosis by elevated ROS levels has been highlighted as the central mechanism responsible for the positive effects of monoclonal antibodies 85 and tyrosine kinase inhibitors 86 , which represent the core of targeted cancer therapy 87

doi: 10.1007/S13593-015-0287-0/TABLES/2 63 FathiA.ZahediM.TorabianS.KhoshgoftarA

Recent systematic reviews of means to prevent and treat acute radiodermatitis describe management strategies in detail and include the following recommendations1,16: - Wash the irradiated areas with a mild shampoo or soap to prevent superinfection