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Platinum (Pt) nanozymes have emerged as promising therapeutic agents capable of mimicking both antioxidative and pro-oxidative enzymatic activities, owing to their partially filled d-orbitals and accessible multivalent states, thereby enabling precise regulation of cellular redox homeostasis

Although disulfide bonded ESSE can be reduced by GSH via thiol-disulfide exchange [220], it most commonly decomposes to ESH and a highly reactive sulfenic acid intermediate (ESOH) [221]

At basal or moderate levels these species have various physiological functions

MFF is the target of miR-340-5p, which negatively regulates MFF expression in PAMSCs under hypoxia (Huang et al., 2022)

Monoclonal antibodies act by freeing T lymphocytes from their negative regulation thus suppressing cancer evasion of the immune system (292,293)