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Description

Nature 413 , 171174 (2001)

In nausea during pregnancy, it has been reported to be as effective as dimenhydrinate or pyridoxine (vitamin B6), with fewer adverse effects

Think of it like a brick wall

All of these drugs have high toxicity, low efficiency, side effects, and high costs (Barrett & Croft, 2012

It appears that LTE 4 functions through one or more receptors distinct from cysLT 1 /cysLT 2 , with some evidence that the orphan receptor GPR99 and the ADP receptor P2Y 12 may function as LTE 4 receptors