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FRET investigation toward DNA tetrahedron-based ratiometric analysis of intracellular telomeraseactivity

INTRODUCTION Aging is associated with the systemic accumulation of damage, leading to a gradual loss of function, deterioration of organismal health, and an increased mortality rate 1

Additional associations with DRB3*0101, DRB1*0301, DQA1*0501, DQB1*0201 and DRB1*1301, and DQA1*0103 and DQB1*0603 have been reported (Donaldson & Norris, 2002)

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Moreover, in vitro experiments in astrocytes found this effect to be specifically induced by Efavirenzs primary metabolite but not the parent compound