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111 Another study has shown that the hypoxic environment upregulates the expression of HIF-1a, which activates the BMP4/SMAD signaling pathway, leading to an increase in ALP content and enhanced expression of osteogenic-related factors OCN and OPN, thereby promoting the osteogenic differentiation of BMSCs

Its most visible effects include stimulating collagen synthesis, reducing fibrosis, and promoting hair follicle activity, but its deeper mechanisms involve DNA repair, anti-inflammatory regulation, and systemic tissue remodeling that extends well beyond skin-deep benefits

Here are some possible benefits of including beef in your diet

2020 [cited 2024 Jul 13]

This process leads to tissue remodeling and tightening, improving tone and elasticity