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For an effective, etiology-driven pain treatment in PD individuals, it is essential to distinguish between nociceptive, neuropathic and nociplastic pain types by means of detailed history taking and PD-specific scales and questionnaires

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Chlorpromazine and promethazine (C+P) have been demonstrated to induce hypothermia in rodents for decades, however, the optimal dosage of this combination of drugs in human remains unclear

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