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Bhat, R

As ion channels are important therapeutic targets and many ion-channel drugs have already been approved for clinical trials, ORF3a is another good antiviral drug target 144

The present study fills the missing mechanistic gap by identifying FABP5 as an upstream driver of this process

Interestingly, with progressive increase in IOP, autophagy is initially activated in the dendrites of RGCs and protects cells, but its subsequent activation in the cytoplasm disrupts homeostasis and induces cell death 21,22,70,71,72

These findings demonstrated that the Si-based agent suppressed LPO production through its antioxidant ability