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Maintenance dosing with 60 mg vials Once you have titrated to your target dose, the 60 mg vial becomes straightforward: At a 10 mg maintenance dose, you need roughly 9 vials per year

PMC 6761819

Because the Fc domain is translated directly upstream of a peptide linker and N-terminus of the FGF21 variant, the N-terminus is protected from degradation by dipeptidyl peptidase (DPP) enzymes (296)

Additional information Peer review information Nature Communications thanks Fabian Filipp and William Gallagher and the other anonymous reviewer(s) for their contribution to the peer review of this work

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