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Studies have also revealed that extravasation of lymphoid cells mediated by the vascular and intracellular adhesion molecules VCAM-1 and ICAM-1 is a seminal event in the pathophysiology of multiple sclerosis

Considering the well-described contribution of fibroblasts in the development of fibrosis, their role in other biological events is often neglected

Peptide therapy should be individualized and integrated into a comprehensive strategy that includes nutrition, exercise, sleep optimization, stress management, and metabolic health assessment

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