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They found that Nrf2 deficiency could exacerbate NIHL as auditory brainstem response (ABR) threshold shifts of the Nrf2 / mice was significantly larger than the wild-type mice at 7 days post-exposure

PMID: 123 WuLLiLLiSLiuLXinWLiCet al

Building on this concept, Bing et al

It helps us identify which areas or systems may need extra support and move beyond a general, one-size-fits-all approach

Many of these new substances appear so fast and with little efficacy support in the literature making it difficult for anti-doping authorities to properly evaluate and consider if they are a problem from the standpoint of performance enhancement