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Mass Spectrometry (MS) Alignment: We run mass spec diagnostics to confirm the exact molecular weight of each component, ensuring zero degradation or incorrect molecular bonding occurred during the freeze-drying process

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All this happens against the backdrop of, and can be modified by, the microorganisms that colonize the ocular mucosa long term, or that are simply transient passengers introduced from the environment

This modulation, in addition to the AIE-induced DNA hypermethylation of the Bdnf exon IV promoter, results in reduced BDNF, which contributes to the development of anxiety-like behaviors and increased voluntary alcohol consumption in adulthood (40, 41) (Figure 3A)

All experiments were performed under standard laboratory conditions (SATP)