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Patients with fatigue unresponsive to oral supplementation and normal B12 labs warrant functional assessment

Hair and skin improvements typically develop over 4 to 8 weeks

It is currently unknown what concentration atorvastatin can reach in muscle cells, but concentrations in blood plasma have been found to be as high as ~334 nM for very high clinical doses (80 mg/day) 39

The sheer complexity and short half-life of most ROS species complicate their measurement, yet such biomarkers are essential for patient stratification and response monitoring

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