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the fat layer is consistent, accessible, and easy to pinch Anterior thigh practical for self-injection, though typically more sensitive than the abdomen Outer upper arm (lateral deltoid fat) requires a second hand or assistance

While some studies show a good correlation between an unfractionated heparin or low molecular weight heparin-calibrated anti-Xa activity assay and other more specific measures of drug concentration including mass spectroscopy, the gold standard for determining DOAC concentration, caution is advised because of differences in chromogenic substrates and other variables, and local laboratories must validate assays before their general use9,41-43

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