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A genetic study found that the interstitial deletion of chromosome 4q in a child with autism contributed to hemizygosity of the glutamate receptor AMPA2, glycine receptors GLRB and GLRA3, and neuropeptide receptors NPY1R and NPY5R [75]

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The more active enantiomer, esketamine ( S -ketamine), is also available for medical use under the brand name Ketanest S, [137] while the less active enantiomer, arketamine ( R -ketamine), has never been marketed as an enantiopure drug for clinical use