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By downregulating these molecules, berberine helps prevent inflammatory white blood cells from sticking to and damaging the blood vessel walls

Aquat Toxicol 164:61e71 Ching B, Chew SF, Wong WP, Yuen K, Ip YK (2009) Environmental ammonia exposure induces oxidative stress in gills and brain of Boleophthalmus boddarti (mudskipper)