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doi: 10.1016/j.tube.2018.04.009 35 RandallPJHsuNJQuesniauxVRyffelBJacobsM

Recent biotechnological advances have revealed diverse functions of this isozyme family, but unveiling the precise physiological role of GSTs is still vexed

helped with the writing of the original manuscript

Maleki, R., Afrouzi, H

This remains an actively moving area, however: on February 27, 2026, the HHS Secretary publicly announced an intent to move roughly 14 of the 19 Category 2-listed peptides, reportedly including ipamorelin and CJC-1295, back toward Category 1 status, and multiple industry and legal-news outlets reported further FDA action in the following months easing Category 2-related restrictions on this group of peptides