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ROS are also known to modulate the activity of voltage-dependent Ca 2+ channels, the most affected being the activity of L-type Calcium channels

130 Less mtDNA copy number and more mtDNA damage are observed in SLE, which is associated with disease durations and prognosis in some SLE patients

Ellis, C

Metabolic abnormalities in PE directly influence lipid metabolic pathways involved in ferroptosis (Kagan et al., 2017)

These findings not only confirm the immunogenicity of ferroptosis but also expand the list of ferroptotic DAMPs responsible for its immunogenicity by adding CRT and ATP to the previously identified danger molecule decorin 20 and various oxidized products, including oxygenated phosphatidylethanolamine 70