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Accumulation of senescent cells in tissues has been associated with age-related functional decline, chronic inflammation, and impaired tissue regeneration

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Proliferative diabetic retinopathy (PDR), which entails a distinctive neovascularization of the retina that is characterized by the invasion of vessels into the vitreous cavity, is coupled with bleeding and scarring around the proliferative channel (Katsura et al., 1998)

Researchers investigate its role in neurobiology and circadian rhythm control