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Apoptosis can be initiated via three principal pathways: the extrinsic (death receptor) pathway, the intrinsic (mitochondrial) pathway, and the endoplasmic reticulum (ER) stress pathway (Figure 2A)

Both laboratories are certified by CLIA, the Clinical Laboratory Improvement Amendments program operated by the US Department of Health and Human Services which oversees approximately 200,000 laboratories in the US, and the tests reported in the paper are CLIA-approved tests

[DOI] [PMC free article] [PubMed] 48.Olson KR, Benowitz NL

N.EichingerS

4b1) and interstitial fibrosis characterized by the presence of many blue colored connective tissue fibers, arrowhead, (Fig