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86,87,88 Although mice can be infected with SARS-CoV-2 by transferring the human ACE2 gene or designing a virus-adapted mouse, no mouse model can simulate all the characteristics of human COVID-19, especially pulmonary vascular disease, hyperinflammatory syndrome, observed in adults and children, respectively

Amongst transporters of unknown function, our screen highlighted SLC25A39, in which SLC25A39 KO cells growth defect is buffered by antimycin or by KO of the mitochondrial iron transporter SLC25A37

To ensure the stability of the entire analytical process and monitor instrument reproducibility, quality control (QC) samples were prepared and inserted throughout the analytical sequence (detailed in the Supplementary Materials)