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Numerous studies have showed that inflammatory reactions weaken tight junctions and further aggravate gut barrier damage (150, 151), which may over time lead to carcinogenesis

Effects of a small-molecule NNMT inhibitor on body weight, glucose tolerance and insulin sensitivity in diet-induced obese mice

As an added bonus, the medication improves the way your body burns energyencouraging it to break down fat instead of storing it

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Starting both agents at lower doses than typically used for monotherapy and escalating more slowly can improve tolerability