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New terms were then developed to extend off the original denition for oxidative stress to account for both the signaling and cytotoxic properties of H 2 O 2

Brice [19]

doi: 10.1128/IAI.71.1.456-464.2003 105 HarthG.Maslea-GaliS.TulliusM

Regulation of NADPH oxidase activity by Rac GTPase activating protein(s)

In addition, activation of runt-related transcription factor-1(Runx1) was shown to enhance the polarization of Th17 cells, which may be related to its interaction with RORt [30]