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Consistent with our in vitro studies, neither N-cadherin nor -catenin ID intensity was significantly affected in Dsp cKO hearts (Fig 3B, B, C, and C)

132 GordonM.TorriV.MigliorS.BeiserJ.FlorianiI.MillerJ.et al (2007)

Although the exact mechanism behind this synergy remains unclear, it may involve destabilization of the bacterial outer membrane through the depolymerase action 135

In vitro experiments have demonstrated that uric acid can cause vascular endothelial cell injury by activating the NLRP3/IL-1 signaling pathway or Nicotinamide adenine dinucleotide phosphate (NADPH) enzymes (17)

Gut microbiota metabolites In recent years, significant findings have been made regarding the role of gut microbiota metabolites in the pathogenesis of MASLD