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Although it does not affect physical health, it can disrupt periorbital esthetics, revealing a tired and aged appearance, thereby affecting the patients quality of life (Citation13)

Table 1 Key mechanisms of metabolic regulation in RA immune cells

10.1371/journal.pone.0068322 PLoS One 108 KatoS.-I.SatoK.ChidaH.RohS.-G.OhwadaS.SatoS.et al (2011)

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Advances in Clinical Chemistry, Volume 85, 2018, Pages 31-69 Effects of L-Carnitine Supplementation on Metabolic Utilization of Oxygen and Lipid Profile among Trained and Untrained Humans