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In contact dermatitis and atopic dermatitis, inhibition of 15-LOX inhibits podosome formation in dendritic cells, downregulates the antigen uptake and cell migration capabilities, and contributes to the alleviation of skin inflammation (Figure 2)

10.1016/j.fitote.2018.05.002 Ho, Y.-T., Liu, I.H., Chang, S.-T., Wang, S.-Y

The exact mechanism by which increased oxidative stress leads to acute hemolysis is unknown, but it results from the inability of G6PD-deficient red blood cells to withstand oxidative damage induced by the triggers mentioned previously