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doi: 10.1016/j.expneurol.2011.01.017 65 O'DonovanS

Chronic Fatigue: A relentless feeling of tiredness that does not improve with rest, which is often caused by the toxic effects of heavy metals on cellular energy production

In most cells, glutathione is found at concentrations of 1-10 mM in the cytoplasm and at lower concentrations in subcellular organelles, including the nucleus, mitochondria, and endoplasmic reticulum