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Developed in the 1990s at the Institute of Molecular Genetics of the Russian Academy of Sciences, it was engineered by extending the naturally occurring immune peptide tuftsin with a C-terminal Pro-Gly-Pro tripeptide to improve metabolic stability dramatically

First, it has a very high prevalence overall, with more than 500 million people estimated to be involved (most of them mostly asymptomatic)

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These strategies aim to stabilize PCs structure against pH-induced degradation, improve solubility, and promote systemic circulation

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