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Previous studies have shown a high degree of overlap between ferroptosis and PD pathophysiological features, such as iron overload, increased lipid peroxidation, reduced glutathione levels, downregulation of the cystine-glutamate antiporter system (System xc-), and decreases in DJ-1 and coenzyme Q10 (CoQ10) 7

MiR-30b protects nigrostriatal dopaminergic neurons from MPP(+)-induced neurotoxicity via SNCA

Studies have shown that PENK demonstrates superior predictive ability over conventional eGFR in septic patients, reliably and sensitively predicting AKI, organ failure, and mortality [101, 104], with plasma PENK levels accurately reflecting glomerular filtration rate

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