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Genetic variant in TP63 on locus 3q28 is associated with risk of lung adenocarcinoma among never-smoking females in Asia

Mutation in these genes results in CS, a profoundly debilitating disorder characterized by short stature, microcephaly, premature aging, neurodegeneration, photosensitivity, vision impairment, hearing loss, and bone and kidney abnormalities (ScheibyeKnudsen et al

[DOI] [PubMed] [Google Scholar] Vieujean S

Interestingly, bone marrow appears to be an important site for vessel co-option in both primary and secondary bone malignancies which, in turn, might explain the development of tumour dormancy in bones and the higher rate of chemoresistance [55,56]

The US Food and Drug Administration approved the peptide for the treatment of types 1 and 2 diabetes in 2005