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8-hydroxy-2'-deoxyguanosine (8-OHdG), which reflects oxidative DNA damage, shows measurable increases around the same timeframe

In this case, because the primary site could not be determined among the various possible carcinoma types, the key focus was to find an effective chemotherapy regimen for the multiple tumors

274 Additionally, using the above model, it was found that palmitic acid (PA) induced ferroptosis through mitochondrial DNA damage activation, resulting in calcification damage of vascular smooth muscle cells

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10.1038/nchembio.2239 123 DongJ.ZhouK.GeX.XuN.WangX.HeQ.et al (2022)