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1998 European Journal of Endocrinology Established Ipamorelin's selective GH release without cortisol/ACTH elevation in swine models Johansen et al

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By blocking IB phosphorylation and preventing p65 nuclear translocation, these compounds downregulate pro-inflammatory cytokines, mitigate neuroinflammation, and improve behavioral outcomes (31, 43, 48, 55, 60)