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They should be avoided losing metal cofactors caused by chelators in the experiment

The frequency of gastrointestinal side effects is higher with retatrutide (nausea affects about 43% vs 12-33% for Mounjaro)

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Erythrocytes play a crucial role in the regulation of eNOS-derived nitric oxide (NO) bioavailability, acting as scavengers of this critical vasodilator with an effect on vascular tone and blood flow [45]