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Within each population, the assessors reviewed different interventions, comparators, and health outcomes, referred to by the acronym PICO

The model of CTR: rAmy (CT-like, PDB: 7TYI) was used as the initial template for the CTR:Cagri/CagriBB complex in the CT-like conformation by replacement of the peptide

The facility also had multiple violations of improper storage of dangerous drugs and controlled substances, which were often in unlocked cabinets or refrigerators in patient-accessible areas

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Their broad substrate range, including drugs and xenobiotics, and their high expression levels at the BBB, contribute a major part to CNS pharmacoresistance [75]