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Additionally, relaxins reduce activation of pro-apoptotic caspases and inflammation by the inhibition of NLRP3 inflammasome and decreased IL-1 and IL-18 levels (215)

Conjugates tend to be more polar compared to the parent compound, more easily excreted, and usually pharmacologically inactive

It is one of the very few animal peptides to contain a D-amino acid (D-alanine at position 2), an unusual feature that is generated post-translationally by enzymatic conversion of an L-alanine encoded in the gene [2]