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Decreased sympathetic nerve firing leads to arterial vasodilation, resulting in reduced total peripheral resistance (TPR), and venodilation, resulting in decreased venous return (preload)

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Acknowledgements This work is part of the activities of the bo Akademi University Foundation (SA) funded Centre of Excellence in Research Materials-driven solutions for combating antimicrobial resistance (MADNESS) and aligned with the activities of the strategic research profiling area Solutions for Health at bo Akademi University [Research Council/Academy of Finland, # 336355]