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576 It is noteworthy that compared with normal mice, SIRT3-deficient mice can cause increased oxidation of fatty acid in heart, which is due to the high acetylation modification and high activity of -HAD and LCAD

Consistent with this finding, 40 mg/kg 48c significantly reduced BUN and creatinine levels after IRI (Fig

Disclosures: Yianni Protopapadakis: Nothing to Disclose, Mark Russo: Nothing to Disclose 1344 DEFINING THE ROLE OF LIVING DONOR LIVER TRANSPLANT IN THE ERA OF MACHINE PERFUSION FOR DONATION AFTER CIRCULATORY DEATH Daniel Lai 1 Therese Bittermann 2 Samir Abu-Gazala 2 Peter Abt 2 , 1 Hospital of the University of Penn, 2 Perelman School of Medicine Background: There has recently been renewed interest in expanding donation after circulatory death (DCD-LT) and living donor liver transplantation (LDLT) programs to expedite transplant at low Model for End-stage Liver Disease (MELD) scores

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Patients who do not tolerate GLP-1 medications: those who had gastrointestinal side effects from semaglutide or tirzepatide and want to understand other options to discuss with a provider