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2), we considered the trajectory of the miRNAtrigger duplex and how it might position the RNA flanking the trigger site

Even in this the above study 69% of the people said that they had no improvement, 31% had a different outcome

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Arch Neurol 60:10821088 Sarchielli P, Di Filippo M, Candeliere A, Chiasserini D, Mattioni A, Tenaglia S, Bonucci M, Calabresi P (2007) Expression of ionotropic glutamate receptor GLUR3 and effects of glutamate on MBP- and MOG-specific lymphocyte activation and chemotactic migration in multiple sclerosis patients