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Description

Thyroid patients should use methylcobalamin or adenosylcobalamin because hypothyroidism often impairs the methylation pathways needed to convert cyanocobalamin into its active form

Another cause of B12 deficiency is its impaired absorption in the gut, in such conditions as pernicious anemia, Crohns disease, celiac disease or surgeries that involve gastric bypass, and result in the lack of intrinsic factor

A transdermal formulation of an MAOI may provide a treatment option that may mitigate some of the risks associated with oral MAOIs, including certain adverse events as well as dietary interactions