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Globally, ASD affects approximately 1 in 100 children (World Health Organization, 2021), with a prevalence of 2.51% children, with a male to female ratio of 3:1in Riyadh, Saudi Arabia (AlBatti et al., 2022)

Studies often report the anode placement over the frontal cortex while the cathodal electrode placement reports are more inconsistent, however, there are reports of inflammation reduction and neuroprotective effects by cathodal stimulation (97)