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Hersh, J

While the GEM studies included patients with moderate to severe COPD, the GOLDEN studies also included very severe patients, with lower post-bronchodilator baseline FEV 1 % predicted, background LABA use, and high CV risk

Dendritic cells (immune system cells that present antigens to T cells) expressing IDO can limit tryptophan supply to T cells in the extracellular matrix, thus limiting T-cell response to tumor growth [127]