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Description

Typically, lactylation induces an open chromatin state, facilitating the binding of transcription factors and the transcription machinery, thereby activating gene expression

Compr Physiol (2017) 8(1):35169

Nasu, E

On the other hand, downregulation of NAMPT mRNA and protein by stable shRNA transfection reduced the tumorigenicity and stemness properties of these cells

Pharmacol Res Perspect 10:e00977 [DOI] [PMC free article] [PubMed] [Google Scholar] 51.Nasiri E, Alizadeh A, Roushandeh AM, Gazor R, Hashemi-Firouzi N, Golipoor Z (2019) Melatonin-pretreated adipose-derived mesenchymal stem cells efficeintly improved learning, memory, and cognition in an animal model of Alzheimers disease