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Surgical options include total thyroidectomy or lobectomy

This is one analysis's framing rather than settled industry consensus, but it's directionally consistent with separate reporting on site burden

Pegylated arginine deiminase (ADI-PEG-20), which duplicates arginine and increases tumor stress and cytotoxicity, increased the number of tumor-infiltrating T cells in phase I studies and was safe in combination with anti-PD-1 antibody, but with an increased risk of neutropenia

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