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Untargeted metabolomics analysis To comprehensively profile the vaginal metabolome, high-resolution liquid chromatography with mass spectrometry (LCMS) was performed on the Thermo Fisher Scientific platform (Ottawa, Canada)

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Predetermined safety criteria were also met, including subjects baseline concerns regarding constipation, weight loss and blood lipid concentrations

The drug resistant, MDA-MB-231 cell line, characterized as invasive ductal carcinoma, exemplifies an aggressive form of triple-negative breast cancer (TNBC) that does not express estrogen receptor (ER), human epidermal growth factor 2 (HER2), or progesterone receptor (PR), categorizing the cells as HER2 /PR /ER subtype [26]