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in contrast, GSS knockout depletes GSH but still permits glutamate consumption for -glutamyl-peptide synthesis, and does not alter ferroptosis sensitivity under cystine starvation

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Increased basal ganglia iron levels in Huntington disease

Importantly, the MT protein in the immune system may not function properly if either zinc or methionine are deficient in the diet [108, 109]

doi: 10.1016/j.mehy.2014.09.012 308 GougeonM-LPoirier-BeaudouinBDurantJLebrun-FrenayCSadiHSefferVet al