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The nanoparticles were synthesized using a double emulsion-solvent evaporation method, then functionalized with albumin to enhance BBB permeability

First, the relatively small sample size in each group may constrain the generalizability of the conclusions, despite rigorous statistical validation and repeated experimental replicates

These differences might be due to intrinsic biological characteristics of each cell line, which may confer differential properties to tumor cells in response to pharmacological challenges in specific manners [43]

Eur J Microbiol Immunol (Bp)

For example, a 0.5 mg daily dose becomes 0.25 mg in the morning and 0.25 mg in the evening